What is typically a sign of a second degree injury in any tissue?

A second-degree injury, also known as a moderate severity injury, typically involves damage that extends beyond just minor tissue, often affecting deeper structures. This type of injury is characterized by notable physical signs and symptoms that reflect the extent of tissue damage. Among these, the presence of blisters indicates that the injury has damaged the protective layers of the skin and possibly deeper tissues, which is a hallmark of second-degree injuries. Additionally, significant pain usually accompanies this level of injury because of the involvement of nerve endings and the inflammatory response triggered by tissue damage.

Blisters are a result of fluid accumulation beneath the skin's surface, which occurs as a protective response to injury. Along with blisters, the severe pain experienced is due to inflammation and nerve involvement in the area affected by the tissue damage. This combination of symptoms—blisters and significant pain—accurately reflects the characteristics of a second-degree injury, making it the correct choice among the options presented.

Other options suggest either very mild symptoms or severe conditions without the appropriate physical signs, which do not align with the manifestations of a second-degree injury.