How is necrosis most accurately characterized?

Necrosis is most accurately characterized as the death of tissue. This process occurs when cells are damaged beyond repair due to factors such as lack of blood supply, infection, toxins, or trauma. When necrosis happens, it leads to the breakdown of cellular structures and the eventual death of the affected tissue, which can compromise function and lead to further complications in the surrounding areas.

Increased blood flow to tissues is typically associated with inflammation or healing processes, not necrosis. Healthy cell regeneration suggests the active repair and renewal of cells, which is the opposite of what occurs in necrosis. Temporary swelling and inflammation can be part of the body’s response to injury, but they do not define necrosis, instead representing a protective and healing response. Thus, necrosis is fundamentally about the irreversible damage and death of cells, making it an important concept in understanding various medical conditions and injuries.